From the eMedicine Article on Shwachman-Diamond Syndrome:
Alter et al (1998) report that the projected median survival age is older than 35 years for all patients with SDS. For those patients whose course is complicated by aplastic anemia, the median survival age is 24 years, while those patients whose course is complicated by leukemia have a median survival age of 10 years.
Showing posts with label Life Expectancy. Show all posts
Showing posts with label Life Expectancy. Show all posts
Saturday, February 9, 2008
More on SDS Life Expectancy from Literature
Another article that lists the median survival as age 35 is titled: Bone marrow failure: a child is not just a small adult (but an adult can have a childhood disease). You can access the full-text article from this link. Click on the title (4th one down) Shwachman-Diamond America Medical Articles
For more resources to quote from, you can also see the new article titled: Shwachman Diamond Syndrome: an emergency challenge which can be accessed at this link: Shwachman-Diamond Syndrome Articles it is the second article on the page—click on the title and the PDF full text will appear. Here is a quote from this article (P 12):
“Alter et Al (1997) reported a median survival age older than 35 years for all patients with SDS. For those patients whose course is complicated by Aplastic anemia, the median survival age is 24 years, while those patients whose course is complicated by leukemia have a median survival age of 10 years.”
For more resources to quote from, you can also see the new article titled: Shwachman Diamond Syndrome: an emergency challenge which can be accessed at this link: Shwachman-Diamond Syndrome Articles it is the second article on the page—click on the title and the PDF full text will appear. Here is a quote from this article (P 12):
“Alter et Al (1997) reported a median survival age older than 35 years for all patients with SDS. For those patients whose course is complicated by Aplastic anemia, the median survival age is 24 years, while those patients whose course is complicated by leukemia have a median survival age of 10 years.”
Life Expectancy in Shwachman-Diamond Syndrome
If you are looking for the words “Life expectancy” you will likely not find it in medical literature…BUT you can find many articles that list median survival and various other stats. Are you reporting for a statistics class or are you doing a project for another class? In Stats, median range is usually given---
In fact, the median survival is listed in literature as 35 yrs. See the article titled: Diagnosis, Genetics, and Management of Inherited Bone marrow failure syndromes which can be accessed from this link: Shwachman-Diamond Syndrome Medical Articles This article includes a section on SDS that says (page 36)
“…and many patients evolve to Aplastic anemia, MDS or Leukemia. The median age for the latter in the literature reports is 18 years, and the age dependant cumulative probability of leukemia is greater than 70%.”
There is a chart in this article on page 30 that lists the following for SDS:
Age at cancer, median (range)-----------------18 (2-43)
Cumulative probability (%) of cancer by age 40-50-----71
Projected median survival age*------------------------35
% alive or dead greater than or equal to 16 y of age----22
In fact, the median survival is listed in literature as 35 yrs. See the article titled: Diagnosis, Genetics, and Management of Inherited Bone marrow failure syndromes which can be accessed from this link: Shwachman-Diamond Syndrome Medical Articles This article includes a section on SDS that says (page 36)
“…and many patients evolve to Aplastic anemia, MDS or Leukemia. The median age for the latter in the literature reports is 18 years, and the age dependant cumulative probability of leukemia is greater than 70%.”
There is a chart in this article on page 30 that lists the following for SDS:
Age at cancer, median (range)-----------------18 (2-43)
Cumulative probability (%) of cancer by age 40-50-----71
Projected median survival age*------------------------35
% alive or dead greater than or equal to 16 y of age----22
Subscribe to:
Posts (Atom)